- Open their season on April 5th in Atlanta
- Open their home season on April 12th versus Milwaukee
- play the AL West in Interleague play, traveling to Texas (May 21-23) and Seattle (June 22-24) while they welcome Oakland (June 15-17) and Anaheim (June 18-20) to town.
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Cubs, Sox Announce Tentative 2010 Schedules
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